Biotransformation of Naringenin by Bacillus amyloliquefaciens Into Three Naringenin Derivatives
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چکیده
منابع مشابه
Abatement by naringenin of doxorubicin-induced cardiac toxicity in rats.
BACKGROUND Doxorubicin is one of the most active cytotoxic agents in current use. It has proven efficacy in various malignancies either alone or combined with other cytocidal agents. The clinical usefulness of the anthracycline drug has been precluded by cardiac toxicity. Many therapeutic interventions have been attempted to improve the therapeutic benefits of the drug. Few, however, have been ...
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Co-culture engineering is an emerging approach for microbial biosynthesis of a variety of biochemicals. In this study, E. coli-E. coli co-cultures were developed for heterologous biosynthesis of the natural product naringenin. The co-cultures were composed of two independent E. coli strains dedicated to functional expression of different portions of the biosynthetic pathway, respectively. The c...
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An inverse association between flavonoid intake and coronary heart disease (CHD) has been suggested by a number of epidemiological studies (42,44,54,78). As a consequence, there is considerable interest in investigating the antiatherogenic nature of these compounds. Flavonoids are naturally occurring molecules abundant in fruit, vegetables, nuts, seeds, and beverages, such as tea and wine. Over...
متن کاملEnhancement of Naringenin Bioavailability by Complexation with Hydroxypropoyl-β-Cyclodextrin
The abundant flavonoid aglycone, naringenin, which is responsible for the bitter taste in grapefruits, has been shown to possess hypolipidemic and anti-inflammatory effects both in vitro and in vivo. Recently, our group demonstrated that naringenin inhibits hepatitis C virus (HCV) production, while others demonstrated its potential in the treatment of hyperlipidemia and diabetes. However, narin...
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O -Alkyl derivatives of naringenin ( 1a - 10a ) were prepared from naringenin using the corresponding alkyl iodides and anhydrous potassium carbonate. The resulting products were used to obtain oximes ( 1b - 10b ). All compounds were tested for antimicrobial activity against Escherichia coli ATCC10536, Staphylococcus aureus DSM799, Candida albicans DSM1386, Alternaria alternata CBS1526, Fusariu...
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ژورنال
عنوان ژورنال: Natural Product Communications
سال: 2019
ISSN: 1934-578X,1555-9475
DOI: 10.1177/1934578x19851971